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Early T-helper 1 Differentiation Is Marked by A Follicular Helper-like Transition: Differential Roles of STAT4 and T-bet

ChEBI2011-12-27 更新2026-07-21 收录

T细胞分化

转录因子功能研究

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https://www.ebi.ac.uk/biostudies/ArrayExpress/studies/E-GEOD-33802 数据链接链接失效反馈

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Early T-helper 1 Differentiation Is Marked by A Follicular Helper-like Transition: Differential Roles of STAT4 and T-bet

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创建时间：

2011-12-27

细胞分化调控

转录因子功能研究

T-cell receptor (TCR) signaling by MHC class-I and -II induces thymocytes to acquire cytotoxic and helper fates via induction of Runx3 or ThPOK transcription factors, respectively. The mechanisms by w

NIAID Data Ecosystem80

Gene expression analysis of mouse pancreas carrying Prox1 ectopic acinar expression

胰腺基因表达

转录因子功能研究

RNA sequencing was used to identify gene expression changes in pancreatic acinar cells with ectopic expression of the homeodomain transcription factor Prox1 Overall design: The pancreas P7 control mic

NIAID Data Ecosystem40

IRF2 is a master regulator of human keratinocyte stem cell fate [RNA-seq]

干细胞干性调控

转录因子功能研究

Resident adult epithelial stem cells maintain tissue homeostasis by balancing self-renewal and provision of differentiated cells. Human epidermal keratinocytes retain stem cell potential in vitro but

NIAID Data Ecosystem20

Foxf2 plays a dual role during TGFb-induced EMT by promoting apoptosis yet enabling cell junction dissolution and migration.. Foxf2 plays a dual role during TGFb-induced EMT by promoting apoptosis yet enabling cell junction dissolution and migration.

上皮-间质转化机制

转录因子功能研究

We have identified the transcription factor forkhead box protein F2 (Foxf2) to be upregulated in its expression during the EMT process and studied its functional contribution to EMT by siRNA-mediated

NIAID Data Ecosystem50

TGF-β specifies TFH versus TH17 cell fates in murine CD4+ T cells through c-Maf (Seq04, scRNA-seq). TGF-β specifies TFH versus TH17 cell fates in murine CD4+ T cells through c-Maf (Seq04, scRNA-seq)

T细胞分化

单细胞转录组学

Naive murine CD4+ T cells were cultured under different polarizing conditions in 96-well plates coated with anti-CD3/anti-CD28 for 0, 0.5, 1.5, 3.5 days, sorted by flow cytometry, and subjected to sin

NIAID Data Ecosystem40

Early T-helper 1 Differentiation Is Marked by A Follicular Helper-like Transition: Differential Roles of STAT4 and T-bet

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