During tumor progression and especially following cytotoxic therapy, cell death of both tumor and stromal cells is widespread. Despite clinical observations that high levels of apoptotic cells correla
We obtained mice with multiple genotypes through mouse mating, and treated mice with tamoxifen at specified time points according to the experimental purpose, so as to make recombinase Cre enter the n
Recurrence and/or metastasis occur in more than half of patients with head and neck squamous cell carcinoma (HNSCC) and pose the greatest threats to long-term survival. The genetic landscape underlyin
Current NPC models cannot reproduce the process of NPC tumorigenesis, which is critical for investigating the functions and mechanisms of the disease-associated factors in this malignancy.So,we aimed
