Luteinizing hormone and melatonin promotes the proliferation of primordial germ cell-like cells by activating the MAPK signaling pathway. Sus scrofa

In vitro differentiation of stem cells into functional gametes is one of the most concerned biomedical topics. Our study showed that both luteinizing hormone and melatonin could significantly promote the proliferation of primordial germ cell-like cells. Herein, we explored to profile the transcriptomic changes in the control, LH and MLT group.