Full Data Set

It is unclear whether hyperhydration induced via glycerol, sodium bicarbonate or a combination of the two is most effective. This study evaluated the effects of glycerol-, sodium bicarbonate-, and glycerol + sodium bicarbonate-induced hyperhydration on measures of fluid retention, blood buffering capacity, and gastrointestinal symptoms at rest, in comparison to a fluid-only control. Eleven healthy participants (six male) completed four trials (randomised, crossover design). Treatments consisted of glycerol-(G) = 1.0 g.kg-1 body mass glycerol; sodium bicarbonate-(SB) = 0.3 g.kg-1 body mass sodium bicarbonate; and combined glycerol and sodium bicarbonate supplementation (G+SB) = 0.3 g.kg-1 body mass sodium bicarbonate + 1.0 g. kg-1 body mass glycerol; and a fluid only control (CON) = 25 mL.kg1 body mass artificially sweetened water. At baseline and at 20 min intervals for 180 min, urine samples were collected and analysed for volume, colour, and specific gravity, and gastrointestinal symptoms and body mass were quantified. At 60 min intervals, capillary blood was analysed for pH, blood bicarbonate concentration and plasma volume change. Compared to CON, fluid retention was significantly higher with G+SB from 120-180 min, SB from 120-140 min, and G from 160-180 min (p