CD8+ T cells are important effectors of adaptive immunity against pathogens, tumors, and self antigens. Here, we asked how human cognate antigen-responsive CD8+ T cells and their receptors could be id
CD8+ T cells that recognize the IPSINVHHY peptide presented by HLA-B*35:01 were isolated form PBMCs using peptide-HLA tetramers. The T cell receptor alpha and T cell receptor beta chain was sequenced.
Quantitative detection and characterization of antigen-specific T cells are crucial to our understanding of immune responses as well as the development of new immunotherapies. Herein, we report a spat
Determining the frequency of activation induced marker (AIM) antigen specific T cells to several commonly encountered antigens in healthy control and Parkinson disease individuals. DMSO samples used f