Fig files for contractility paper

An active-stress model of tissue contractility incorporating strain-adaptive contractility control was considered. Informed by experimental systems, we consider three paradigm tissue types: a contractile ball, a contractile shell with elastic core and a contractile sheet thus capturing key geometries of commonly investigated organoids and tissues. We predict the deformations and stresses that are generated in these tissues, which reveals a potential contractility-based control signal from an active shell to an elastic core. We find that introducing a strain-adaptive feedback into the contractility force acts to both effectively stiffen the tissue and to decrease its apparent compressibility, with the feedback sensitivity determining the new effective stiffness. In two-dimensions this effective stiffening is significantly more apparent and can even generate anomalous Poisson’s ratios. These figures were produced from analytical solutions which were attainable due to the simplified geometries under consideration.