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IGF1-receptor signalling attenuates the age-related decline of diastolic cardiac function

ChEBI2012-07-31 更新2026-07-21 收录

心血管衰老机制

IGF-1信号通路

数据链接：

https://www.ebi.ac.uk/biostudies/ArrayExpress/studies/E-GEOD-32936 数据链接链接失效反馈

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资源简介：

IGF1-receptor signalling attenuates the age-related decline of diastolic cardiac function

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创建时间：

2012-07-31

神经氧化应激

IGF-1信号通路

Fig1a) Neuron viability measured as percentage of GFP positive cells cultured ± astrocytes after treatment with H2O2. N: neurons, NA: neurons + astrocytes. Names for each file refer to the related fig

NIAID Data Ecosystem100

IGF-1, IGF-1receptor mRNA, and L-[U-14C]-phenylalanine incorporation into proteins, in confluent non-proliferating L6 skeletal muscle cells.

骨骼肌代谢

IGF-1信号通路

Cells were amino acid refed at High AA concentrations (9 mM) with or without presence of inhibitors of molecules in the IGF-1receptor signaling pathway (mean±SE, n = 4-5/group).

NIAID Data Ecosystem40

Endothelial expression of ZBTB16 protects against cardiac aging

心血管衰老机制

细胞功能研究

Endothelial expression of ZBTB16 protects against cardiac aging

ChEBI2025-10-24 更新20

Senescence as a novel mechanism involved in β-adrenergic receptor mediated cardiac hypertrophy

心血管衰老机制

衰老药物干预

Pathological cardiac hypertrophy used to be elucidated by biomechanical, stretch-sensitive or neurohumoral mechanisms. However, a series of hints have indicated that hypertrophy process simulates sene

Figshare2017-08-05 更新50

The 32 miRNAs and their corresponding miRNA gene clusters.

心血管衰老机制

差异表达miRNA分析

Approximately half of the miRNAs (32 out of 65 miRNAs) that were differentially expressed in the old heart belong to 11 miRNA gene clusters. These 32 miRNAs had greater than 1.5-fold change in old (O)

Figshare2015-12-02 更新30

IGF1-receptor signalling attenuates the age-related decline of diastolic cardiac function

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