Acetic acid stress Acididesulfobacillus acetoxydans

We investigated the stress response to acetic acid of Acididesulfobacillus acetoxydans, an acetotrophic aSRB. A. acetoxydans was cultivated in laboratory-scale bioreactors at its optimum pH (pH 5.0). Triplicate “stressed” reactors were spiked with 7.5 mM of acetic acid and compared with “controls” (non-spiked) triplicate reactors for physiological, transcriptomic and core lipid changes. Both control and acetic acid spiked cultivations were performed in triplicate. Samples for transcriptome analyses were taken at two time points after spiking, i.e. 2.5 and 26 hours after spiking. The first time-point sample was withdrawn from both spiked and control reactors, whereas the second time-point was only taken at 26 hours after spiking. This dataset incorporates 9 transcriptome datasets.