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The FK1 domain of FKBP51 in complex with the macrocyclic SAFit analog 12h/k

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Protein Data Bank Japan2025-03-19 更新2026-08-24 收录
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The FK1 domain of FKBP51 in complex with the macrocyclic SAFit analog 12h/k Descriptor: 3-cyclohexyl-23,24-dimethoxy-17-methyl-11,22-dioxa-5-aza-23lambda5,24lambda5-diphospha-2,23lambda5-diphosphapentacyclo[21.2.1.01,18.05,10.018,23]hexacosa-18,24-diene-4,12-quinone, Peptidyl-prolyl cis-trans isomerase FKBP5 Authors: Meyners, C, Buffa, V, Walz, C, Hausch, F. Deposit date: 2024-09-09 Release date: 2025-01-15 Last modified: 2025-03-19 Method: X-RAY DIFFRACTION (1.36 Å) Cite: Conformational Plasticity and Binding Affinity Enhancement Controlled by Linker Derivatization in Macrocycles. Angew.Chem.Int.Ed.Engl., 64, 2025

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2024-09-09
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