Protective mechanisms of Qingda granule in hypertensive kidney injury: Focus on ERK/RSK1-mediated mitochondrial protection

The objective of this study was to compare blank control mice (WT) with AngII-induced hypertensive mice (M). Angii-induced hypertensive mice (M) and QDG intervention group (QDG); Different genes expressed in renal tissue and identify new targets for reversing hypertension-induced renal damage. RNA sequencing was performed on the renal tissues of WT, Model and QDG groups (n = 3 in each group) at 6 weeks of age to identify different expression genes and related pathways.