ALTERATIONS IN THE LIPID PROFILE IN SUBCLINICAL HYPOTHYROIDISM AND THEIR CARDIOMETABOLIC SIGNIFICANCE

Subclinical hypothyroidism (SCH) is characterized by elevated serum thyroid-stimulating hormone (TSH) levels in the presence of normal circulating free thyroxine ($FT_4$) and triiodothyronine ($FT_3$) concentrations. In contemporary endocrine cardiology, subtle thyroid dysfunction is increasingly recognized as a key driver of systemic metabolic shifts [1]. This study provides a comprehensive analysis of lipid profile alterations in patients with SCH, elucidating the pathophysiological mechanisms that accelerate atherogenesis and elevate long-term cardiovascular risk based on the latest global clinical evidence [2].