Enhancing reprogramming towards human expanded pluripotency
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Enhancing reprogramming towards human expanded pluripotency
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2026-03-12
相关数据集
Identification of SSEA-1 expressing enhanced reprogramming (SEER) cells in porcine embryonic fibroblasts
Previous research has shown that a subpopulation of cells within cultured human dermal fibroblasts, termed multilineage-differentiating stress enduring (Muse) cells, are preferentially reprogrammed in
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Chromatin Accessibility Dynamics during Chemical Induction of Pluripotency [RNA-seq]. Chromatin Accessibility Dynamics during Chemical Induction of Pluripotency [RNA-seq]
Chemical induction of pluripotency (CIP) is an ideal way to reprogram cell fate, but remains poorly understood. Here we report the development of an efficient CIP protocol and the chromatin accessibil
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Chemical reprogramming of human blood cells into hCiPS cells [bulk ATAC-seq]
Chemical reprogramming offers a fundamentally innovative approach for generating human pluripotent stem (hCiPS) cells using small molecules. Our recent studies showed that this approach was highly eff
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Self-Renewing Presomitic Mesoderm Progenitor Lines Reprogrammed from human urine cells [xxx scRNA-seq]. Self-Renewing Presomitic Mesoderm Progenitor Lines Reprogrammed from human urine cells [xxx scRNA-seq]
Vertebrae formation is the defining feature of all vertebrates1,2. Yet, each vertebrate species appears to have a unique timing mechanism for forming somites along the vertebral column3-5. Human verte
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Cecr2 promotes somatic cell reprogramming as a downstream target of SALL4 [ChIP-seq]
Sall4 is among one of the most important reprogramming factors. However, the underline molecular mechanisms for such importance remains unclear. In this report, we first described the gene expression
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