The increasing prevalence of antibiotic resistant pathogens poses a serious threat to global health. This study aims to investigate the response and adaptation of carbapenem resistant K. pneumoniae un

NIAID Data Ecosystem00

Development and application of CRISPR/Cas9-assisted genome-editing tools for comprehensive investigation the role of efflux pumps in Mycobacterium abscessus

细菌耐药性机制

外排泵毒力功能

Using CRISPR/Cas9-assisted genome-editing tools, we constructed 68 efflux pump mutants of M. abscessus and investigated their roles in drug resistance and virulence. We found that different efflux pum

NIAID Data Ecosystem00

Exogenous pyruvate promotes gentamicin uptake to kill antibiotic-resistant Vibrio alginolyticus

细菌耐药性机制

细菌代谢干预治疗

Exogenous pyruvate promotes gentamicin uptake to kill antibiotic-resistant Vibrio alginolyticus

integrated proteome resources30

DataSheet_4_Persistent ciprofloxacin exposure induced the transformation of Klebsiella pneumoniae small colony variant into mucous phenotype.csv

细菌表型转换

细菌耐药性机制

IntroductionSmall colony variant (SCV) is a bacterial phenotype closely related to persistent and recurrent infections. SCVs are mutations that occur within bacterial populations, resulting in a chang

NIAID Data Ecosystem00

The structural model of a homodimeric D-Ala-D-Ala metallopeptidase, VanX, from vancomycin-resistant bacteria

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