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Diastereoselective Bromocyclization of O‑Allyl‑N‑tosyl-hydroxylamines

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Figshare2016-02-19 更新2026-04-29 收录
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https://figshare.com/articles/dataset/Diastereoselective_Bromocyclization_of_i_O_i_Allyl_i_N_i_tosyl_hydroxylamines/2433757
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The intramolecular bromoamination of O-allyl-N-tosyl-hydroxylamines results in the formation of isoxazolidines via selective 5-endo-tet cyclization. This process occurs trans-selectively in high yield and diastereoselectivity. The obtained bromo-isoxazolidines provide access to other useful building blocks, such as 2-azido-aminoalcohols, diaminoalcohols, and aziridines.
创建时间:
2016-02-19
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