Downregulation of human SPARCL1 in malignant carcinomas.

NIAID Data Ecosystem2026-03-11 收录

癌症基因表达下调

恶性肿瘤分子机制

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https://figshare.com/articles/dataset/Downregulation_of_human_SPARCL1_in_malignant_carcinomas_/12351683 数据链接链接失效反馈

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资源简介：

Downregulation of human SPARCL1 in malignant carcinomas.

创建时间：

2020-05-21

Effect of DNMT3A R882H mutation or WT expression on global DNA methylation patterns of hematopoietic stem/progenitor cells with NRAS G12D co-transduction (eRRBS)

恶性肿瘤分子机制

DNA甲基化与白血病

DNA Methyltransferase 3A (DNMT3A) is frequently mutated in various hematopoietic malignancies; however, the underlying oncogenic mechanisms remain elusive. Here, we report that DNMT3A mutational ‘hots

NIAID Data Ecosystem120

HSF1 drives a transcriptional program distinct from heat shock to support highly malignant human cancers

癌症转录调控

恶性肿瘤分子机制

This SuperSeries is composed of the following subset Series: GSE38232: HSF1 drives a transcriptional program distinct from heat shock to support highly malignant human cancers [gene expression] GSE389

NIAID Data Ecosystem90

Multi-omics analysis of RNA binding, splicing and turnover alterations induced by mutant U2AF1 in myeloid malignancies.

RNA剪接异常

恶性肿瘤分子机制

Splicing factor mutations are common among cancers, recently emerging as drivers of myeloid malignancies. U2AF1 carries hotspot mutations in its RNA binding motifs; yet how they affect splicing and pr

NIAID Data Ecosystem50

H3K4me3 ChIP-Seq analysis of LSKs isolated from WT and Mll-PTD knock-in heterozygous mice

表观遗传调控

恶性肿瘤分子机制

The MLL-PTD mutation is found in patients with MDS and AML, and not in other haematological malignancies. Previously, we showed that Mll-PTD knock-in heterozygous mice present with several MDS-associa

NIAID Data Ecosystem100

Exome sequencing data from two myelosarcomas

肿瘤基因组学

恶性肿瘤分子机制

Isolated myeloid sarcoma (MS, i.e. acute myeloid leukemia without detectable bone marrow infiltration) is rare and most patients subsequently develop overt AML. We prospectively performed whole exome

NIAID Data Ecosystem90

Downregulation of human SPARCL1 in malignant carcinomas.

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