Transcriptomic and epigenetic profiling of fibroblasts in Idiopathic Pulmonary Fibrosis (IPF) [RNA-seq]

RNA sequencing was used to identify differentially expressed genes (DEGs) which could reflect early disease in IPF. Overall design: Primary human lung fibroblasts were isolated directly from the upper half of the upper lobe from human lungs, there are 4 healthy controls and 5 IPF patients to identify differentially expressed genes between IPF patients and healthy controls.