Exploring the effect of XingNaoKaiQiao acupuncture stimulation in rats with cerebral ischemia injury. Exploring the effect of XingNaoKaiQiao acupuncture stimulation in rats with cerebral ischemia injury

To reveal the molecular signatures of XingNaoKaiQiao acupuncture on the Cerebral cortex of rats with cerebral ischemia/reperfusion injury, we performed bulk RNA sequencing. Overall design: The rats were randomly divided into sham group, model group, rt-PA group and acupuncture + thrombolytic group. The model was middle cerebral artery occlusion (MCAO) thromboembolism model, in which the thrombolytic group underwent thrombolytic intervention at 6 hours post model establishment and the acupuncture + thrombolytic group underwent acupuncture intervention at 2 hours, Xingnaokaiqiao acupuncture stimulation was performed at the Shuigou (GV26) and left Neiguan (PC6) acupoints.