BIOGRID CURATED DATA FOR GRH1 (Saccharomyces cerevisiae (S288c))

Protein-Protein, Genetic, and Chemical Interactions for GRH1 (Saccharomyces cerevisiae (S288c)) curated by BioGRID (https://thebiogrid.org); DEFINITION: Acetylated cis-Golgi protein, involved in ER to Golgi transport; homolog of human GRASP65; forms a complex with the coiled-coil protein Bug1p; mutants are compromised for the fusion of ER-derived vesicles with Golgi membranes; protein abundance increases in response to DNA replication stress

由BioGRID（https://thebiogrid.org）编纂的GRH1（酿酒酵母S288c）蛋白质-蛋白质、遗传学和化学相互作用数据集；定义：乙酰化型顺式高尔基蛋白，参与内质网至高尔基体的运输；人类GRASP65的同源物；与螺旋状蛋白Bug1p形成复合物；突变体在内质网起源的囊泡与高尔基体膜融合方面受损；在DNA复制压力响应下蛋白质丰度增加。