EPI-Clone dataset: Human total bone marrow

This is the dataset supporting the EPI-Clone manuscript: Targeted single cell methylation profiling of bone marrow was performed with the scTAMseq method. Two experiments are included: bone marrow from a 71-year-old male patient and from a 77-year-old male patient. Dataset is an R Data File (RDA) with two seurat objects which each include the following assays, reductions and metadata: <b>SEURAT OBJECTS:</b><b> </b>patient1: cells obtained from the 71-year-old patient patient2: cells obtained from the 77-year-old patient <b>ASSAYS:</b><b> </b>AB: Antibody expression data DNAm: DNA methylation data, containing binary observations (0: amplicon not observed, i.e. dropout or absence of DNA methylation, 1: amplicon observed, i.e. DNA methylation). See the paper on scTAMseq <b>DIMENSIONALITY REDUCTION</b><b> </b>methPCA: PCA performed on the DNAm data methUMAP: UMAP computed on the DNAm data cloneUMPA: UMAP computed by EPI-Clone <b>METADATA</b> SurfacePhenotype: Surface phenotype annotation CelltypeMeth: Cell type annotation according to UMAP based on methylation data PerformanceNonHhaI: Performance of the control amplicons in that cell NchrY: Number of reads on the ChromosomeY amplicons EPIClone: Cluster annotation computed by EPI-Clone