Transcriptional profiling of Mms21 deleted (mms21Δ/Δ) mutant Candida albicans strains

Mms21 deletion in Candida albicans resulted in invasveness and filamentatation in YPD media at 30 degrees Celsius. Wild type SN148 do not make any Filaments in YPD at 30 degrees Celsius. The aim was to look for transcription profiling mms21 dleleted mutant against wild type to find genes up and down regulated in the mutant especially thoseones critical for filamentation 2 samples were analyzed. Cells were grown in YPD media at 30 degrees celcius to OD 0.8. MMS21 deleted strain (mms21Δ/Δ) vs wild type (SN148)