Analysis of genetic interactions between the serotonin – GOA-1(Gαo) and EGL-30(Gαq) signaling pathways.

The number of Dar animals was scored as a percentage of the total. Drug treatments were as described in the Methods. Values are means +/− the standard error. No Dar animals were observed in uninfected tph-1(mg280), tph-1(n4622) or egl-10(n692) single mutants.a = p≤0.0001 relative to RE:::EGL-30*.b = p≤0.01 relative to RE::EGL-30*;tph-1(mg280).c = p≤0.001 relative to RE:::EGL-30*.d = p≤0.05 relative to RE::EGL-30*;tph-1(mg280).e = p≤0.0001 relative to wild type on 10% M. nematophilum.