Effect size to measure amphetamine-induced displacement of [¹¹C]FLB 457 BP_ND.

% values shown are mean ± standard deviation (SD); Δ BPND is amphetamine-induced displacement of [11C]FLB 457 BPND [13,15]; BASE T-RT is test-retest variability [11C]FLB 457 BPND under baseline conditions [14]; Post-AMPH T-RT is test-retest variability of [11C]FLB 457 BPND under post-amphetamine conditions (this study, Table 4); Effect size (d) is computed as mean Δ BP ND/ mean pooled variability; Pooled variability was calculated as the square root of (BASE T-RT2 + POST-AMPH T-RT2)/2 to incorporate both the baseline and post-amphetamine test-retest data.