Stereocontrolled Synthesis of Kalihinol C
收藏NIAID Data Ecosystem2026-03-10 收录
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We report a concise chemical synthesis of kalihinol C via a possible biosynthetic intermediate, “protokalihinol”, which was targeted as a scaffold en route to antiplasmodial analogs. High stereocontrol of the kalihinol framework relies on a heterodendralene cascade to establish the target stereotetrad. Common problems of regio- and chemoselectivity encountered in the kalihinol class are explained and solved.
创建时间:
2017-03-03



