Polycomb group (PcG) proteins control organism development by regulating the expression of developmental genes. Transcriptional regulation by PcG proteins is achieved at least partly through the PRC2-
Kindlin-2, an integrin-interacting FERM-domain-containing protein, has been known to play critical roles for tumor progression. However, the role of Kindlin-2 in renal cell carcinoma (RCC) progression
Our results demonstrated that augmented Kla advances RCC progression by modulating phase separation and thereby regulating the stability of target genes. Article's Experimental Original Data Is Upload