Serotonin 4 (5-HT4) receptor-Gs complex
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Serotonin 4 (5-HT4) receptor-Gs complex Descriptor: CHOLESTEROL, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, ... Authors: Huang, S, Xu, P, Shen, D.D, Simon, I.A, Mao, C, Tan, Y, Zhang, H, Harpsoe, K, Li, H, Zhang, Y, You, C, Yu, X, Jiang, Y, Zhang, Y, Gloriam, D.E, Xu, H.E. Deposit date: 2022-05-16 Release date: 2022-07-27 Last modified: 2025-06-18 Method: ELECTRON MICROSCOPY (3.2 Å) Cite: GPCRs steer G i and G s selectivity via TM5-TM6 switches as revealed by structures of serotonin receptors. Mol.Cell, 82, 2022
5-羟色胺4型(5-HT₄)受体-Gs蛋白复合物 描述:胆固醇、鸟苷酸结合蛋白G(I)/G(S)/G(O)亚基γ-2、鸟苷酸结合蛋白G(I)/G(S)/G(T)亚基β-1…… 作者:Huang, S、Xu, P、Shen, D.D、Simon, I.A、Mao, C、Tan, Y、Zhang, H、Harpsoe, K、Li, H、Zhang, Y、You, C、Yu, X、Jiang, Y、Zhang, Y、Gloriam, D.E、Xu, H.E 存档日期:2022-05-16 发布日期:2022-07-27 最后修改日期:2025-06-18 实验方法:电子显微镜(分辨率3.2 Å) 引用文献:G蛋白偶联受体(GPCRs)通过TM5-TM6开关调控G_i与G_s选择性:5-羟色胺受体结构解析揭示的机制. 《分子细胞》, 82卷, 2022年



