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Mechanistic study of lipopolysaccharide-induced protection in macrophages against antitumor drugs

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This project aims to investigate the protective mechanism of low-dose Lipopolysaccharide (LPS) on RAW264.7 macrophages treated with antitumor drugs, specifically Adriamycin. We utilized LC-MS/MS based quantitative proteomics to identify differentially expressed proteins. The results provide insights into how LPS induces drug efflux and enhances macrophage survival through the regulation of drug resistance-associated proteins.

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2026-01-26
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