Transcription Factors Dlx1/2 Are Required for Making All Interneurons in the Olfactory Bulb [Pax6]
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https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE121213
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Purpose: To assess changes in gene expression profiles from the E16.5 wild type littermate controls cortex and Pax6 sey/sey mutant mice cortex. Methods: Total RNA was isolated and sequenced using an Illumina Hi-seq 2500. Raw data was analyzed using TopHat. Genes were considered significantly changed which perform P value <= 0.05. Results: Compared to controls, 173 genes were significantly down regulated, and 245 genes were up regulated in the RNA expression level of the mutant cortex. Cortex RNA profiles of E16.5 Wild type mouse brain and Pax6 sey/sey mutant mice brain.
创建时间：
2019-03-21
