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Crystal structure of human MTH1 in complex with compound MI1014

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Protein Data Bank Japan2024-03-27 更新2026-03-21 收录
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Crystal structure of human MTH1 in complex with compound MI1014 Descriptor: 7,8-dihydro-8-oxoguanine triphosphatase, N4-cyclopropyl-5-ethyl-6-(4-methylpiperazin-1-yl)pyrimidine-2,4-diamine Authors: Peng, C, Li, Y.H, Cheng, Y.S. Deposit date: 2019-04-17 Release date: 2020-10-28 Last modified: 2024-03-27 Method: X-RAY DIFFRACTION (1.9 Å) Cite: Inhibitor development of MTH1 via high-throughput screening with fragment based library and MTH1 substrate binding cavity. Bioorg.Chem., 110, 2021
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2019-04-17
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