Essential nature of known exported proteins.

Validated exported proteins for which data are available are categorized as “non-essential”, “not tested”, or “essential” [8], [16], [33], [41]–[44]. Proteins in bold are P. falciparum-specific. *) The lack of sequence information for the P. berghei orthologue of pfa0210c did not allow us to attempt to delete the gene, however, the conserved nature of the gene and the export of the protein product, similar to pfd0495c, pfc0435w and pf14_0607, make it highly likely that the protein is essential. **) Essential nature of pfd0495c was established separately (Tamez and Haldar, unpublished).