five

Tandem Conjugate Reduction−Aldol Cyclization Using Stryker's Reagent

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NIAID Data Ecosystem2026-03-06 收录
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https://figshare.com/articles/dataset/Tandem_Conjugate_Reduction_Aldol_Cyclization_Using_Stryker_s_Reagent/3739206
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Conjugate reduction by Stryker's reagent to form copper enolates, followed by intramolecular aldol cyclization, successfully generated five- and six-membered carbocycles in one pot efficiently. This tandem reaction is generally diastereoselective and provides good yields of the β-hydroxyketones without any dehydration at low temperatures.
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2016-08-20
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