DataSheet_1_CT, MRI, and PET/CT imaging features of thoracic spine epithelioid hemangioma: a retrospective observational study.doc

IntroductionEpithelioid hemangioma (EH) is an intermediate locally aggressive tumor that consists of epithelioid cells and endothelial cell differentiation, which can occur at any age, but is most common between the ages of 30 and 40 years. EH in the thoracic spine is rare, and accurate diagnosis is critical to treatment planning. Our aim was to explore the imaging and clinical data of thoracic spine EH to improve the understanding of this rare disease.MethodsFrom January 1, 2018 to June 30, 2023, a database of thoracic spine masses was retrospectively reviewed. Five patients with histologically proven thoracic spine EH and complete imaging available were identified and analyzed. Computed tomography (CT) and magnetic resonance imaging (MRI) findings were evaluated separately by two radiologists with more than 10 years of experience. Positron emission tomography (PET)/CT was conducted by two nuclear medicine diagnostic technologists with at least 5 years of experience.ResultsThe patients included three male and two female patients aged 23 to 56 years (mean age was 38.4 ± 14.3 years). All patients underwent CT, MRI, and 18F-FDG PET/CT examination before treatment. Four patients were limited to one vertebral involvement, only one patient had multiple vertebral involvement, and all tumors involved the accessories, including one involving the posterior ribs. The maximum diameter of the tumor ranged from 2.7 to 4.3.ConclusionsCT, MRI, and 18F-FDG PET/CT findings of thoracic spine EH have certain characteristics, and understanding these imaging findings will help to obtain accurate diagnosis before surgery.

上皮样血管瘤（EH）是一种介于局部侵袭性肿瘤，由上皮样细胞和内皮细胞分化构成，其发生可遍布各年龄段，但以30至40岁之间最为多见。胸椎上皮样血管瘤较为罕见，准确的诊断对于治疗计划的制定至关重要。本研究旨在探讨胸椎上皮样血管瘤的影像和临床数据，以增进对该罕见疾病的理解。方法：自2018年1月1日至2023年6月30日，对胸椎肿块数据库进行了回顾性审查。共识别出5例经组织学证实的胸椎上皮样血管瘤患者，并对其完整的影像资料进行了分析。由两位具有超过10年经验的放射科医生分别对计算机断层扫描（CT）和磁共振成像（MRI）的发现进行了评估。由两位至少拥有5年经验的核医学诊断技术人员进行了正电子发射断层扫描（PET）/CT检查。结果：包括3名男性和2名女性患者，年龄在23至56岁之间（平均年龄为38.4±14.3岁）。所有患者均在治疗前行CT、MRI和18F-FDG PET/CT检查。其中4例患者仅涉及单个椎体，仅1例患者涉及多个椎体，所有肿瘤均涉及附件，其中1例涉及后肋。肿瘤的最大直径范围为2.7至4.3厘米。结论：胸椎上皮样血管瘤的CT、MRI和18F-FDG PET/CT表现具有一定的特征，对这些影像发现的了解将有助于在手术前获得准确的诊断。