Using conditional independence tests to elucidate causal links in cell cycle regulation in Escherichia coli. Kar et al.

The dataset accompanies the publication "Using conditional independence tests to elucidate causal links in cell cycle regulation in Escherichia coli" by Kar et al. The data originates from measurements reported in [S. Tiruvadi-Kirshnan et al., Cell Reports,2022]. The column names 'Tx' correspond to the timings of different events in the cell cycle. Possible values for x are 'ri1', 'rt', 'c', 'n', 'd', 'ri2', and 'ri3' - corresponding to the initiation of replication, termination of replication, the onset of constriction based on the phase image, the onset of constriction based on Ypet-FtsN signal, cell division, initiation in one daughter cell, and initiation in the other daughter cell, respectively. The times are in minutes. Time zero corresponds to cell birth. Negative times correspond to events in the previous cell cycle. The column names "Lx" list cell lengths at different cell-cycle events. Additionally, Lb corresponds to cell birth. All lengths are in micrometers. Pos, Channel, Cell identify a particular cell cycle. Birthfr and Divfr denote the frame when a cell is born and when it divides, respectively. Each frame is 4 mins apart and is relative to the start of the experiment. So, a cell with Birfr = 20 is born 80 min after the experiment has started. Mothcell is the value of the Cell column of the mother cell. The mother cell also must have the same Pos, and Channel as the daughter cell. For thymine mutant, the file is named Figure_6_STK37 as we perform experiments on the STK37 E. coli strain.本数据集配套Kar等人发表的学术论文《使用条件独立性测试（conditional independence tests）阐明大肠杆菌（Escherichia coli）细胞周期调控中的因果关联》。其数据来源于[S. Tiruvadi-Kirshnan等人2022年发表于《Cell Reports》的实验测量结果]。列名'Tx'对应细胞周期内不同事件的时间节点，x的可选取值为'ri1'、'rt'、'c'、'n'、'd'、'ri2'和'ri3'，分别对应复制起始、复制终止、基于相位图像的收缩启动、基于Ypet-FtsN信号的收缩启动、细胞分裂、一个子细胞的复制起始以及另一个子细胞的复制起始。时间单位为分钟，时间零点对应细胞诞生时刻，负值代表上一个细胞周期内发生的事件。列名"Lx"记录了不同细胞周期事件发生时的细胞长度，其中Lb对应细胞诞生时的细胞长度，所有长度单位均为微米（μm）。Pos、Channel、Cell三列用于唯一标识某一特定细胞周期；Birthfr与Divfr分别表示细胞诞生和细胞分裂所处的帧编号，每帧间隔4分钟，且以实验启动时刻为时间基准。例如，若某细胞的Birthfr取值为20，则该细胞于实验开始后80分钟时诞生。Mothcell字段为母细胞的Cell列取值，且母细胞需与对应子细胞具有完全相同的Pos和Channel属性。针对胸腺嘧啶突变株的数据集文件命名为Figure_6_STK37，因为本实验使用的是STK37大肠杆菌菌株。