Signaling by GPCR

This event has been computationally inferred from an event that has been demonstrated in another species.<p>The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.<p><a href='/electronic_inference_compara.html' target = 'NEW'>More details and caveats of the event inference in Reactome.</a> For details on PANTHER see also: <a href='http://www.pantherdb.org/about.jsp' target='NEW'>http://www.pantherdb.org/about.jsp</a>

该事件系基于另一物种中已证实的类似事件，通过计算方法进行推断得出。推断依据为 PANTHER 中的同源映射。简而言之，对于所有涉及的物理实体（包括输入、输出和催化剂）均存在映射同源/同源异构体（对于复合物而言，至少75%的组成部分必须具有映射）的反应，将其推断至另一物种。同时，对于这些事件，亦进行高级事件的推断，以便于更便捷的事件导航。<p>有关 Reactome 中事件推断的更多细节及注意事项，请参阅：<a href='/electronic_inference_compara.html' target = 'NEW'>事件推断详情及注意事项</a>。欲了解更多关于 PANTHER 的信息，请访问：<a href='http://www.pantherdb.org/about.jsp' target='NEW'>PANTHER 简介</a>。