The impact of Interleukin 27 on the expression of immune checkpoint molecules and their ligands in/on peripheral blood lymphocytes in a group of healthy people and patients with chronic lymphocytic leukemia - cytometric data

The study aimed to determine the impact of interleukin 27 on the expression of immune checkpoint molecules and their ligands in/on peripheral blood lymphocytes subjected to cell culture. Such lymphocytes came from people from a healthy population and from people suffering from chronic lymphocytic leukemia. During the study, the expression of the following antigens was determined: LAG3, HLA-DR, CTLA4, CD80, IFN-g, IL-4, TIM-3, GAL-9, PDL-1, PD-1, IDO-1, GITR in the CD4+, CD8+ and CD19+ cell populations.