Crystal structure of wild type human Lipocalin PGDS in complex with substrate analog U44069

Crystal structure of wild type human Lipocalin PGDS in complex with substrate analog U44069 Descriptor: (5E)-7-{(1R,4S,5S,6R)-5-[(1E,3S)-3-hydroxyoct-1-en-1-yl]-2-oxabicyclo[2.2.1]hept-6-yl}hept-5-enoic acid, Lipocalin-type prostaglandin-D synthase, THIOCYANATE ION Authors: Lim, S.M, Chen, D, Teo, H, Roos, A, Nyman, T, Tresaugues, L, Pervushin, K, Nordlund, P. Deposit date: 2013-01-03 Release date: 2013-03-20 Last modified: 2023-09-20 Method: X-RAY DIFFRACTION (1.88 Å) Cite: Structural and dynamic insights into substrate binding and catalysis of human lipocalin prostaglandin D synthase. J.Lipid Res., 54, 2013

本数据集为野生型人脂笼蛋白（Lipocalin）型前列腺素D合酶（PGDS）与底物类似物U44069结合的晶体结构。配体描述：(5E)-7-{(1R,4S,5S,6R)-5-[(1E,3S)-3-羟基辛-1-烯-1-基]-2-氧杂双环[2.2.1]庚-6-基}庚-5-烯酸、脂笼蛋白型前列腺素D合酶以及硫氰酸根离子（THIOCYANATE ION）。作者：Lim, S.M.、Chen, D.、Teo, H.、Roos, A.、Nyman, T.、Tresaugues, L.、Pervushin, K.、Nordlund, P.。提交日期：2013-01-03，发布日期：2013-03-20，最后修改日期：2023-09-20。实验方法：X射线衍射（X-RAY DIFFRACTION），分辨率1.88埃（Å）。引用文献：Structural and dynamic insights into substrate binding and catalysis of human lipocalin prostaglandin D synthase. J.Lipid Res., 54, 2013，其中文译名为《人脂笼蛋白前列腺素D合酶的底物结合与催化的结构及动态研究》。