Healthy donors and patients with primary immune thrombocytopenia Raw sequence reads

NIAID Data Ecosystem2026-05-26 收录

免疫性血小板减少症

B细胞受体

数据链接：

https://www.ncbi.nlm.nih.gov/sra/SRP181079 数据链接链接失效反馈

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资源简介：

BCR sequencing of peripheral B cells in patients with primary immune thrombocytopenia

创建时间：

2019-01-23

Peyer’s Patch Germinal Centers Select Innate-like BCRs

B细胞受体

肠道免疫

Primary B cell receptor (BCR)/antibody variable region exons are generated by V(D)J recombination with junctional diversification creating immensely diverse antigen contact-encoding CDR3s. While most

NIAID Data Ecosystem160

The role and mechanism of miR-557 in inhibiting the differentiation and maturation of megakaryocytes in immune thrombocytopenia

免疫性血小板减少症

miRNA功能机制

Specific miRNA in immune thrombocytopenia (ITP) was screened to explore its intervention effects and mechanisms in ITP. MTT assay and CFSE staining were used to detect the effects of gradient concentr

DataCite Commons2024-03-21 更新80

Novel germline alleles predicted by cAb_Rep database. Novel human B cell receptor germline alleles

B细胞受体

祖先等位基因

cAb_Rep is a public database that contains 293 B cell repertoires from 108 human healthy, vaccinated, and autoimmune disease donors. The database includes a total of ~4.2 and 1.2 million curated full

NIAID Data Ecosystem60

First line treatment of adult patients with primary immune thrombocytopenia: a real-world study

免疫性血小板减少症

治疗方案

Immune thrombocytopenia (ITP) is an autoimmune disease with a mild to severe risk of bleeding complications. First line treatment includes corticosteroids, immunoglobulins, or other. In this large coh

DataCite Commons2024-02-20 更新90

Immune cells surveil aberrantly sialylated O-glycans on megakaryocytes to regulate platelet count

免疫性血小板减少症

血小板生成

Immune thrombocytopenia (ITP) is a common platelet disorder in pediatric patients. Pediatric and adult ITP have been associated with sialic acid alterations, but the pathophysiology of ITP remains elu

NIAID Data Ecosystem70

Healthy donors and patients with primary immune thrombocytopenia Raw sequence reads

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