An SP110-SP100 axis is a critical regulator of PML body dynamics and mitotic fidelity
收藏NIAID Data Ecosystem2026-05-10 收录
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资源简介：
Genome-wide CRISPR inhibition screens in WT and SP110 KO in human RPE1 cells +/- innate immune stimulation with ppp-RNA identifies SP110 as a negative regulator of SP100-induced genotoxicity. RNA sequencing demonstrates the relationship between SP110 and SP100 is not dependent on global transcriptional changes.
创建时间：
2026-01-26
