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Specific binding ratios of [<sup>123</sup>I]ADAM in brains of BALB/c mice with or without CT26/<i>luc</i> tumors determined with <i>ex vivo</i> autoradiography.

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Ex vivo autoradiography was performed at 90 mins post i.v. injection of 1 mCi [123I]ADAM/0.1 ml. Specific binding ratio = (target – cortex)/cortex. (OT = olfactory tubercle; LS = lateral septal nucleus; ThN = thalamic nuclei; SN = substantia nigra; HN = hypothalamic nuclei). *p<0.05, **p<0.01 vs. wild-type; #p<0.05, ##p<0.01, ###p<0.001 vs. never, <$>\scale30%\raster="rg2"<$>p<0.05, <$>\scale30%\raster="rg2"<$><$>\scale30%\raster="rg2"<$>p<0.01, <$>\scale30%\raster="rg2"<$><$>\scale30%\raster="rg2"<$><$>\scale30%\raster="rg2"<$>p<0.001 vs. after. Data are means±S.E. n = 3/group. Experiments were repeated twice.

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2012-07-13
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