Clinical information and predisposing factors in 117 patients with cryptococcal meningitis.

NOTE: aPredisposing factors including immunocompromising diseases (liver cirrhosis, chronic kidney diseases, autoimmune diseases, malignancies, solid organ transplantation, diabetes mellitus), and corticosteroid or immunosuppressive medications, and idiopathic CD4+ T lymphocytopenia. Some patients had more than one predisposing factors.bDefined as receiving prednisone of a mean minimum dose of 0.3 mg/kg/day, or equivalent doses of other corticosteroids for >3 weeks.cImmunosuppressive agents including cyclosporine, tripterygium glycosides, vincristine, etc.dPatients with one or more conditions including disturbance of consciousness, cerebral herniation, and death were classified as severe cases.