The sqt-1 mutation enhances the Muv phenotype of integrated strains.

The sqt-1(jg52) mutation was introduced to suppress the Rol phenotype of the integrated strains. sqt-1 effect is different in each integrated line. There was no difference between jgIs25 and sqt-1;jgIs25 (P = 0.834), but the Muv ratio of jgIs6 is changed in the sqt-1 mutant background (P = 0.00163). In particular, jgIs26 which is another integration line of LET-23::hEGFR-TK[T790M-L858R] exhibited the dramatic increase of Muv in the sqt-1 mutant background (Psqt-1 allowed us to score the multivulva more clearly compared to the rolling strain.