3D Printing of Personalised Carvedilol Tablets Using Selective Laser Sintering - Underlying Data

Underlying μCT Data for "3D Printing of Personalised Carvedilol Tablets Using Selective Laser Sintering"

by Atabak Ghanizadeh Tabriz, Quentin Gonot-Munck, Arnaud Baudoux, Vivek Garg, Richard Farnish, Orestis L. Katsamenis, Ho-Wah Hui, Nathan Boersen, Sandra Roberts, John Jones, and Dennis Douroumis

published in MDPI pharmaceutics
In section: Physical Pharmacy and Formulation, Recent Non-oral Dosage Form Development: Focus on 3D-Printed Formulations

The micro- and macro-porosities of representative 3D-printed tablets at 25%, 40%, and 55% laser intensities was measured. SLS-printed components were also characterised by means of X-ray microfocus computed tomography (μCT). Imaging was performed at the University of Southampton’s μ-VIS X-ray Imaging Centre (www.muvis.org) using a customised μCT scanner optimised for 3D X-ray histology (www.xrayhistology.org). The system, which is based on Nikon’s XTH225ST system (Nikon Metrology UK Ltd.)

Data index

20230206_XRH_3299_OLK_PHAR08603-DOSF_40.zip

Dataset (including ORS Dragonfly analysis file) of object printed at 40% laser power
10 µm voxel size isotropic

20230206_XRH_3299_OLK_PHAR08616-DOSF.zip

Dataset (including ORS Dragonfly analysis file) of object printed at 55% laser power
10 µm voxel size isotropic

20230206_XRH_3299_OLK_PHAR08616-DOSF_25.zip

Dataset (including ORS Dragonfly analysis file) of object printed at 25% laser power
10 µm voxel size isotropic

SLS-3DP_OLK-CorrectRes.xlsx

Analysis results & graphs

X-ray CT analysis conducted using Dragonfly software (v. 2022.1.0.1231; Object Research Systems (ORS) Inc, Montreal, Canada, 2020; software available at http://www.theobjects.com/dragonfly