Long-read sequencing of GSDIa genome editing
收藏NIAID Data Ecosystem2026-05-10 收录
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https://www.ncbi.nlm.nih.gov/sra/SRP601259
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The primary goal was to characterize large genomic insertions at Cas9 mediated double strand breaks by either targeted homology dependent recombination or non-homologous end-joining with an AAV vector carrying a human G6pc transgene. PacBio long-read sequencing technology was used to sequence dual unique molecular identified tagged PCR amplicons generated from extracted liver DNA of treated mice.
创建时间:
2026-01-01



