Comparison of performance of recognition of exposed and buried residues using proposed Cα-based approach, all-atom models generated starting from Cα positions in relation to all-atom crystal structures.

The structures with Cα atom positions only were subjected to side chain modelling using two different methods (MODELLER and Scwrl3). Solvent accessible and buried residues were subsequently identified using these all-atom models and the proposed method (Cα only) were compared with results from using the all-atom crystal structures.