IL-36 and IL-17A Cooperatively Induce a Psoriasis-like Gene Expression Response in Human Keratinocytes
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https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE160904
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资源简介:
In this study we tested interactions between IL-36 and IL-17A in human keratinocytes. 24 hours of IL-36 stimulation in keratinocytes promoted IL-36, IL-17C, and characteristic psoriasis-related molecule expressions in normal human epidermal keratinocytes in dose-dependent manners as measured by mRNA and protein quantification. 12 cultured samples of human keratinocytes stimulated with IL-36 and IL-17 family cytokines, as single cytokines and also as a combination were evaluated by gene expression profiling with Affymetrix U133 2.0Plus arrays
创建时间:
2022-07-01



