Complexity-Enhancing Acid-Promoted Rearrangement of Tricyclic Products of Tandem Ugi 4CC/Intramolecular Diels−Alder Reaction
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https://figshare.com/articles/dataset/Complexity_Enhancing_Acid_Promoted_Rearrangement_of_Tricyclic_Products_of_Tandem_Ugi_4CC_Intramolecular_Diels_Alder_Reaction/3042823
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资源简介:
The unexpected rearrangement of 2,3,7,7a-tetrahydro-3a,6-epoxyisoindol-1-one products of the tandem Ugi 4CC/intramolecular Diels−Alder reaction in 85% H3PO4 was
discovered to provide diastereomerically pure tricyclic bislactam lactone-containing natural product-like products in
high yield. Mechanistic rationale for the observed rearrangement was proposed and has been tentatively confirmed by
additional experiments.
创建时间:
2016-02-29



