Factors Associated With Covid-19 Severity: A Retrospective Analysis Of Reported Cases In Sabah, Malaysian Borneo

The objective of this study is to understand the epidemiology of COVID-19 in Sabah from March 2020 through October 2021 and to determine the factors associated with COVID-19 severity. The data used in this study were provided by the Surveillance Unit, Sabah State Health Department, Ministry of Health Malaysia. Individuals aged ≤5 years old and ≥ 65 years old (AOR=1.87, 95% CI: 1.77–1.99), non-citizens of Malaysia (AOR=1.46, 95% CI: 1.30–1.64), male gender (AOR=1.06, 95% CI: 1.01–1.12), native Sabahan (AOR=1.30, 95% CI: 1.19–1.42), presence of symptoms of COVID-19 infection (AOR=23.33, 95% CI: 20.75-26.23), presence of comorbidity (AOR=1.80, 95% CI: 1.67-1.94), high exposure risk of COVID-19 infection (AOR=0.44, 95% CI: 0.28-0.71), and incomplete COVID-19 vaccination (AOR=8.53, 95% CI: 7.35-9.89) were statistically significantly associated with developing severe COVID-19 infection.本研究旨在阐明2020年3月至2021年10月马来西亚沙巴州新型冠状病毒肺炎（COVID-19）的流行病学特征，并明确与COVID-19重症相关的影响因素。本研究使用的数据由马来西亚卫生部沙巴州卫生部门监测单元提供。经统计学分析，以下因素与重症COVID-19感染的发生存在显著关联：年龄≤5岁或≥65岁人群（调整后比值比（adjusted odds ratio, AOR）=1.87，95%置信区间（confidence interval, CI）：1.77–1.99）、非马来西亚籍人士（AOR=1.46，95%CI：1.30–1.64）、男性（AOR=1.06，95%CI：1.01–1.12）、沙巴原住民（AOR=1.30，95%CI：1.19–1.42）、存在COVID-19感染症状（AOR=23.33，95%CI：20.75–26.23）、合并基础疾病（AOR=1.80，95%CI：1.67–1.94）、COVID-19感染高暴露风险（AOR=0.44，95%CI：0.28–0.71）以及未完成COVID-19全程疫苗接种（AOR=8.53，95%CI：7.35–9.89）。