Streptococcus pneumoniae is a major cause of serious infections such as pneumonia and meningitis in both children and adults worldwide. Here, we describe the development of a high-throughput genome-wi

NIAID Data Ecosystem20

Haemophilus influenzae Tn-seq. Haemophilus influenzae RdAW

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免疫耐受机制

Transposon insertion site sequencing (Tn-seq) reads from Haemophilus influenzae grown in different conditions: chemically defined medium, sub-MIC clarithromycin (two concentrations), and clarithromyci

NIAID Data Ecosystem10

Tn-seq of Salmonella Typhimurium under iron-restriction with oxidative stressor

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沙门氏菌应激响应

We exposed a highly saturated Tn5 mutant library of S. Typhimurium to an in vitro condition containing both a H2O2 (2.5 mM) and an iron chelator (100 uM Dip)

NIAID Data Ecosystem30

Enhanced genome-wide knockout screens in bacteria with CRISPR base editors

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CRISPR碱基编辑技术

Genome-wide knockout or knockdown screens have become powerful tools for the investigation of genotype-to-phenotype relationships. In bacteria, these screens commonly rely on transcriptional repressio

NIAID Data Ecosystem10

Tn-seq experiments ldcV mutant. Vibrio cholerae strain:N16961

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