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CD3254-RXRa Axis Promotes Chemical Reprogramming via RNA Exosome-Mediated MMVL30 Degradation and Inflammation Suppression [RNA-seq]

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NIAID Data Ecosystem2026-05-01 收录
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We show that CD-RXRa axis significantly promotes mouse chemical reprogramming of fibroblasts. To identify the molecular mechanisms of CD-RXRa axis in chemical reprogramming, we compared reprogramming efficiency for CD-treated, Rxra-OE and shE3 cells. We then performed RNA-seq for 3 different treatments of 6 samples. Overall design: Comparative gene expression profiling analysis of RNA-seq data for CD-treated, Rxra-OE and shE3 reprogramming intermediates.

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2023-08-03
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