Chk1 inhiitors decrease the expressions of STAT3 downstream target genes in multiple myeloma cells. Chk1 inhiitors decrease the expressions of STAT3 downstream target genes in multiple myeloma cells
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Study #1: U266 cells were treated with 100 nM PF477736 for 4 hr. Study #2: U266 cells were treated with 100 nM PF477736 for 16 hr. Study #3: KAS/6-1 cells were treated with 50 nM PF477736 or 300 nM CEP3891 for 2 hr. Overall design: RT-PCR profiling of multiple myeloma cells
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2021-05-17
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