Adeno-associated virus (AAV) 9-mediated gene delivery of Nurr1 and Foxa2 cures symptoms and pathologies of Alzheimer disease model mice by suppressing neuro-inflammation and glial pathology.
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https://www.ncbi.nlm.nih.gov/sra/SRP371275
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资源简介：
In this study, AAV9-Nurr1 and AAV9-Foxa2 (or AAV9-Control as sham-operated control) were injected to hippocampus of 15-18 months old 3xTg Alzheimer's disease mice. And mouse hippocampal glia were primarily cultured at postnatal day 1 and forced expression of Nurr1 and Foxa2 with lentivirus (or lenti-Control). Overall design: mRNA profile of 3xTg AD mice hippocampus and hippocampal primary cultured glia.
创建时间：
2022-04-23
